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Antimigraine intermediate
5-Bromo Indole
Halogenated indole used as the cross-coupling and alkylation handle in the eletriptan scaffold.
- CAS No.
- 10075-50-0
- Molecular formula
- C₈H₆BrN
- Mol. weight
- 196.05 g/mol
- Appearance
- Off-white to pale brown crystalline solid
- API target
- Eletriptan hydrobromide (CAS 143322-58-1)
Description
5-Bromo indole is the indole building block that delivers the bromoaryl handle for Suzuki and Heck couplings in eletriptan and other tryptamine-derived APIs.
Applications
- Eletriptan hydrobromide synthesis
- Tryptamine and indole chemistry
